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This reduction in the overall DNA damage load is fundamental to preserving cellular function and preventing the onset of age-related cellular dysfunction ( The direct enhancement of DNA repair capacity by exercise signifies a fundamental mechanism by which exercise combats aging at its very core

It also directly neutralizes free radicals and maintains vitamin C and E activity

Revised Feb

every four weeks), and then at least every 6 12 months once the target has been achieved Probenecid (fully funded) and febuxostat (funded with Special Authority approval) are alternatives for patients who find allopurinol ineffective or intolerable