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Moreover, the role of bile acid receptors such as the Farnesoid X receptor (FXR) and G protein bile acid-activated receptor 1 (GPBAR1) is crucial in regulating inflammatory responses and metabolic disruptions, including lipid imbalances, across both hepatic and neural environments

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UA activates Nrf2 and leads to the upregulation of GCLM gene expression, boosting GSH synthesis and release in astrocytes, which in turn protects glial cells and neighboring neurons [177]

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Choose the Hair Growth Option That's Right for You Topical Minoxidil + Copper Our topical formula is applied directly to the scalp and is ideal for patients who prefer targeted treatment

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doi: 10.3389/fphar.2020.601572 Received 01 September 2020 Accepted 18 November 2020 Published 10 December 2020 Volume 11 - 2020 Edited by Ashok Kumar, University of Florida, United States Reviewed by Justin James Botterill, University of Toronto Scarborough, Canada Wladyslaw Lason, Polish Academy of Sciences (IF PAS), Poland Updates Copyright 2020 Jia, Yin, Li, Guan, Yang, Chen, Zhou and Mao

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