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Frontiers A comprehensive review of Rubia cordifolia L.: Traditional uses, phytochemistry, pharmacological activities, and clinical applications The gut microbiota: a major player in the toxicity of environmental pollutants? npj Biofilms and Microbiomes Frontiers An overview of the ameliorative efficacy of Catharanthus roseus extract against Cd2+ toxicity: implications for human health and remediation strategies Mercury Drug The Leading Drugstore in the Philippines Frontiers Synthesis of vancomycin functionalized fluorescent gold nanoparticles and selective sensing of mercury (II)

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2.2.3 Others Metformin influences the production of advanced glycation end products (AGEs) and the generation of ROS through the activation of AMPK, inhibition of the receptor for advanced glycation end products/nuclear factor kappa B (RAGE/NF-B) signaling pathway, and modulation of gene expression

3.7 Luteolin inhibits thrombus formation in vivo Arterial thrombosis was examined in a mouse model of mesenteric thrombosis induced by ferric chloride ( in vivo experiments were used to evaluate the effect of luteolin on the platelet function

Research indicates that the leakage of iron is associated with neurodegeneration and may exacerbate pathological conditions by inducing inflammatory responses and cellular damage ( During ferroptosis, the deficiency of GPX4 leads to elevated levels of intracellular ROS, triggering oxidative stress (Zheng and Conrad, 2020)