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10.1111/jcmm.15683 Summary Keywords curcumin, epigenetic regulation, RNA methylation, DNA methylation, histone modification, non-coding RNA, drug delivery systems, cancer therapy Citation Smail SW, Bergsten P, Taha KO, Yashooa RK, Hawezy DJ, Abbas MA and Shekha MS (2025) Curcumin: biochemistry, pharmacology, advanced drug delivery systems, and its epigenetic role in combating cancer

Bisdemethoxycurcumin attenuated renal injury via activation of Keap1/Nrf2 pathway in high-fat diet-fed mice

Rather, these processes interact through complex, multicausal pathways involving bidirectional feedback loops between circadian regulation, metabolic status, inflammatory signaling, and environmental exposures