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We nevertheless included the 2YF/2YA mutants in functional assays of G6PD, not to demonstrate a role as a phosphorylation-defective surrogates but to show that G6PD catalytic activity is essential for the Lac-GSTP1-G6PD axis to regulate the pentose phosphate pathway

Accessed 29 May 2021

A cascade mechanism gets initiated leading to the downstream stimulation of chemokine and intracellular adhesion molecule (ICAM) formation following the generation of IL-l and TNF, respectively [185]