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Importantly, these meta-analyses did not always account for baseline selenium status, making it difficult to determine whether supplementation was more beneficial for patients with existing selenium deficiency

Int J Hematol 86(1):8-16, 2007

PLoS ONE 11 , e0147947 (2016)

Increased waist circumference, as a manifestation of central obesity, is considered a predictive surrogate of the severity of LUTS in obese patients (69, 70) and animal models of obesity (71)