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Although its role is not fully understood, NAAG does specifically interact with the NMDA receptor (but not with AMPA or kainate receptors) through which it modulates synaptic plasticity [93]

Speer T, Rohrer L, Blyszczuk P, Shroff R, Kuschnerus K, Krankel N, Kania G, Zewinger S, Akhmedov A, Shi Y, Martin T, Perisa D, Winnik S, Muller MF, Sester U, Wernicke G, Jung A, Gutteck U, Eriksson U, Geisel J, Deanfield J, von Eckardstein A, Luscher TF, Fliser D, Bahlmann FH, Landmesser U

Biochimie 73:13351338

This is the rate-limiting step in glutathione synthesis

Srebp-controlled glucose metabolism is essential for NK cell functional responses