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Emgard J

For first-time users, an 8-week cycle provides an excellent introduction

doi: 10.1016/j.jsxm.2016.01.016 18 GoldsteinILueTFPadma-NathanHRosenRCSteersWDWickerPA

reported that erythrocyte-derived miRNAs, specifically miR-451 and let-7i enriched in HbS RBCs, are translocated into P.f where they bind parasite mRNAs and suppress translation, indicating an intrinsic epigenetic defense mechanism mediated by host miRNAs [208]