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In brief, pathogens are taken into phagolysosomes where enzyme complex NADPH oxidase converts O 2 to a superoxide radical (O 2 ) which, under a dismutase reaction can be converted into hydrogen peroxide (H 2 O 2 ) by enzyme superoxide dismutase (SOD)

In turn, this may increase risk of atherosclerosis, cardiovascular disease, insulin resistance, and Type 2 diabetes

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Production of nitric oxide by glial cells: regulation and potential roles in the CNS

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