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This is particularly noteworthy as current topical treatments for psoriasis may be limited by safety concerns, high costs, or frequent dosing requirements

Addition of BHB increased both the basal and the maximal rate of mitochondrial respiration and enhanced the spare respiratory capacity after short-term (day 3) (Extended Data Fig

Unconjugated bilirubin effectively scavenges singlet oxygen, interacts with superoxide anions and peroxyl radicals, and acts as a reducing substrate for peroxidases in the presence of hydrogen peroxide or organic hydroperoxides (Stocker and Ames, 1987)

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A full description of the mechanism and the state of the research is expanded in a dedicated article on DSIP in the One-Peptides knowledge base