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One of these is the family of trefoil factor peptides. The trefoils are peptides that are protected from degradation in the stomach by their complex, twisted structure

Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: a double-blind, placebo-controlled pilot study

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This can lead to completely skewed data, inflammatory responses in cell cultures, or unexpected molecular interactions