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The judge disagreed, saying evidence presented at the bench trial showed that the vitamin regimen, which counters side effects from the drug, wasnt obvious at the time Lilly was developing Alimta in the late 1990s

However, researchers have proposed that the activation of Nrf2 plays a major role in the antioxidant mechanism for counteracting oxidative stress in neuropsychiatric conditions, mediated by both exogenous and endogenous antioxidants (85)

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