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Excessive lipid peroxidation contributes to plasma membrane damage and further triggering multiple cell death modalities

Heme is the prosthetic group for a number of proteins, including among others hemoglobin, myoglobin, mitochondrial cytochromes, microsomal cytochromes (including cytochrome P450), catalase, peroxidase, tryptophanpyrrolase, prostaglandin endoperoxide synthase, and the soluble form of guanylate cyclase

Role of cyclooxygenase and protein kinase C

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Approaches to past research include analyzing the aqueous humor, which is thought to be a useful way to discover specific molecules that contribute to glaucoma pathophysiology, and a proteomic approach, which has been used to identify proteins that are candidates for making prognoses in glaucoma pathogenesis