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EBioMedicine 102 , 105056 (2024)

Chem Biodivers 5:24652573 Krmer SD, Testa B (2009) The biochemistry of drug metabolism an introduction

A key mechanism is their function as histone deacetylase(HDAC) inhibitors, which epigenetically regulates gene expression in immune cells (Qu et al., 2023)

Recently, immunotherapy, including immune checkpoint inhibitors, has been applied clinically, and complete responses have been achieved in some ICC patients