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The distinction becomes particularly relevant when considering vitro approaches: genetic modification of cells outside the body followed by infusion constitutes gene therapy-mediated cell therapy, such as CAR-T cells, whereas the ASGCT definition classifies this under gene therapy when the genetic alteration is the primary therapeutic mechanism

Also, it has enormous potential for commercial crop protection through PGR spray during stress, which is where future research is needed

In certain cases, ESCRT-III also restricts ferroptotic progression in a FSP1-dependent manner [127, 128]

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