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Discussion There are a few key unsolved issues that impede clinical benefits of AADs in human cancer patients, including understanding of drug resistance, selection of reliable biomarkers, and timeline of treatment, and optimization of combination therapy 5

ChIP-seq library preparation Ten milligrams of frozen tumour tissue was minced and crosslinked using 1% formaldehyde in PBS for 10 min at RT

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doi: 10.3390/ijerph18041578