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2025-01-07

Eur J Clin Invest 2000;30(10):91529

The most severe mutations generally fall into Class 1, characterized by severe enzyme deficiency ( 200% of normal activity)

Next, we studied this cellular model by examining the main pathophysiological features observed in FRDA fibroblasts, specifically frataxin expression and iron accumulation, and the effect of ALA on these iNs