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Cobalamin supplements are well tolerated regardless of the administration route

This makes the research peptide a promising candidate for further research

Therefore, in intestinal endocrine L-cells, BA act through the opposite effects on TGR5 and FXR to regulate the production and secretion of GLP-1, thereby maintaining weight loss and improving glucose tolerance

The N-terminal domain consisting of 80-odd residues adopts a thioredoxin-like fold and harbors the G-site, which binds glutathione with a number of highly conserved residues as well as with ionic bonds from Asp101 and Glu 131 in the adjacent subunit (Sinning et al., 1993)

121 (3), 24372444 (2022) A