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Moreover, significant associations were observed between age of onset and severe hypoglycemia history, as well as between diabetes duration and visual memory performance, reinforcing the role of these variables in shaping cognitive outcomes

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On the other hand, because DMSO is a cell-permeable cryoprotectant and considered to exert its cryoprotective effect both intra- and extracellularly, non-cell-permeable ZIL theoretically cannot completely replace DMSO