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In vitro experimental investigation, it has been observed that the administration of 20 g/mL of Car A resulted in the cure of breast cancer via the activation of apoptotic and antioxidant genes ( 4.2.2.4.5 p-Coumaric acid This acid is most commonly found in cereals, vegetables and fruits

Effects of pyrroloquinoline quinone (PQQ) and PQQ-oxazole on DNA synthesis of cultured human fibroblasts

10.1146/annurev-phyto-082712-102340 126 Pislewska-BednarekM.NakanoR

doi: 10.1007/s00296-022-05146-9 252 PretoriusEVenterCLaubscherGJKotzeMJOladejoSOWatsonLRet al

These are some examples of how OoC technology can represent a next-generation preclinical testing tool, moving beyond conventional toxicology toward precision immuno-oncology, where patient-derived chips could guide therapeutic decisions and dose optimization while reducing reliance on animal models