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10.1016/0893-133x(95)00137-3 73 MarkK

Once in the body, creatine is primarily taken up by muscle tissue, with approximately 1-2% per day non-enzymatically converting to creatinine, which is then excreted by the kidneys

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Therefore, the need for normal breed-specific reference ranges has been emphasised for comparison of pathological changes caused by cardiac disorders." (9) Jacobson, J.H., et al., An echocardiographic study of healthy Border Collies with normal reference ranges for the breed

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