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Li W, Li X, Su J, Chen H, Zhao P, Qian H, Gao X, Ye Q, Zhang G, Li X

demonstrated that lactate acts as a signaling molecule in endothelial cells by inducing HIF-1 activation and promoting tumor angiogenesis

Multilayer-coated liquid crystalline nanoparticles for effective sorafenib delivery to hepatocellular carcinoma

Theranostics 9 , 38403852 (2019)

In hyperuricemia models, this process activates the innate immune system, resulting in elevated serum levels of LPS and pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF-) (Xu D