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Therefore, postnatal L-carnitine deficiency may lead to impaired fatty acid oxidation, resulting in clinical manifestations of hypoglycemia, hypothermia, acidosis and infection

However, it has previously been demonstrated that TMAO supplementation markedly downregulated the expression of critical enzymes in bile acid biosynthesis (CYP7A1 and CYP27A1) and hence reduced the size of the bile acid pool (Koeth et al., 2013)

[11] Levine LA, Burnett AL

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Nutritional Supplements - It is commonly incorporated into meal replacement shakes and dietary supplements