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Low levels can lead to fatigue, weakness, low mood, and neurological symptomsoften going unnoticed without proper testing

The mean concentration-time profiles showed low and similar intra-subject variability and were close to superimposable for the three treatments (Figure 1)

Studies have shown that purified IgG extracted from FMS patients with FMS specifically binds to rat dorsal root ganglia (DRG), with nine distinct binding clusters identified, suggesting that autoimmune antibodies may participate in FMS mediated by SCGs (110)