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Low glutathione-to-GSSG ratios suggest higher oxidative burden and may warrant twice-daily dosing rather than single-dose protocols

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Although the clinical practice guidelines did impact injection use, given the high costs of these injections and their questionable clinical efficacy , further interventions beyond publishing clinical practice guidelines are needed to encourage higher-value care for patients with knee osteoarthritis . Corticosteroid injections in the hip and knee: Not as safe as doctors think In October 2019, doctors published their study: Intra-articular Corticosteroid Injections in the Hip and Knee: Perhaps Not as Safe as We Thought? in the medical journal Radiology .( 7 )