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Clinical judgment and individual patient factors remain paramount, regardless of these categories

The main differences are faster absorption, potentially more intense temporary side effects, and increased pain at the injection site

For retatrutide , Phase 2 trial data published in the New England Journal of Medicine (2023) demonstrated highly significant weight loss outcomes in adults with obesity (without type 2 diabetes)

For instance, the release of antidiuretic hormone (ADH) increases, prompting the kidneys to reabsorb more water back into the bloodstream, which can lead to concentrated urine