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Liquid chromatography tandem mass spectrometry analysis Liquid chromatography tandem mass spectrometry was performed by mixing 50 l of each IgG1 variant (1 mg/mL) with 1 g trypsin dissolved in 100 l 50 mM ammonium bicarbonate (pH 7.8) and incubated ON at 37 C

J Clin Endocrinol Metab 89:48904897

134 These devices are usually custom-fitted by a dentist and are more likely to help people who have mild-to-moderate sleep apnea and are female, younger, and carry less excess weight

The studies in vivo indicated that the GEN-loaded star-shaped copolymer mannitol-functionalized nanoparticles were able to show significantly superior antitumor activity than the linear copolymer mannitol-functionalized nanoparticles and pristine GEN (Wu et al., 2016)

Immunosuppressants such as mycophenolate mofetil and azathioprine reduce disease activity but carry risks of serious infections, liver toxicity, and malignancy