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166 In a randomized controlled trial that enrolled 100 subjects with slightly to moderately high cholesterol levels, 2,000 FUs of nattokinase per day for eight weeks prolonged measures of clotting time (collagen-epinephrine closure time and activated partial thromboplastin time) more than placebo

The findings suggest that initial immune priming via the mRNA vaccination, if followed by SARS-CoV-2 infection, may significantly alter the humoral response, potentially leading to increased production of IgG4 antibodies and a heightened risk of infection, cancer, and autoimmune disease

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A deficiency in folic acid can cause a variety of hematologic complications including megaloblastic and macrocytic anemias