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Encapsulation and delivery strategies Phytochemicals low solubility in aqueous medium restrict their applications in food and pharmaceutical products, thus, encapsulation is a tool to enhance their stability, bioavailability and bio-efficacy by protecting them against adverse environmental conditions, improving retention time and controlled release at target sites (82, 83)

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Oral administration of 2 g of vitamin C in healthy populations helped to reduce aggregation platelet and arterial stiffness, however, the exact mechanism has not been fully explored (Wilkinson et al