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Among these, a few stand out, notably Quin et al., mRNA-based therapeutics: powerful and versatile tools to combat diseases, and Lu et al., Current landscape of mRNA technologies and delivery systems for new modality therapeutics. The proposed review article, titled Beginning of a New Era of Synthetic Messenger RNA (mRNA) Therapeutics: Comprehensive Insights on mRNA Drug Design, Development, and Applications, is uniquely distinguished from the aforementioned reviews due to its explicit focus on current therapeutic and commercial applications, analyzed through published patents and clinical trial records

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More and more evidence shows a close relationship between ERS and autophagy, with autophagy being an important downstream event of ERS [91]