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While B12 is generally safe, caution is needed in specific clinical situations: Lebers Disease (Hereditary Optic Neuropathy): B12 injections are generally contraindicated or should be used with extreme caution, as they may potentially aggravate optic atrophy in this rare condition

In our opinion and considering the aforementioned doubts concerning the reliability of blood vitamin B 12 tests alone, such a re-evaluation is advisable [17,19,56,57,58,59]

ME 12 500MCG INJECTION is not recommended for use in patients allergic to mecobalamin and/or other B12-containing medicines

Human liver arylacetamide deacetylase

What Is Pernicious Anemia and Why Does It Require Injections