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Not only the number of CD68 + cells, but also the percentage of CD68 + cells expressing high levels of IL-6 was reduced (Extended Data Fig

The currently available drugs for the treatment of these diseases often have significant adverse effects, particularly those used in long courses of treatment, ranging from relatively mild (such as nausea or loss of appetite) to severe (such as nephrotoxicity or peripheral neuropathy) (183186)

Low dose naltrexone (LDN) is a term for using naltrexone at a much lower dose than normally prescribed

In addition, studies should investigate HTY effects on microRNA expression and gene regulation using physiologically relevant concentrations

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