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Hundreds of mutations in the SCN1A gene have been found to lead to loss-of-function, and known to cause a spectrum of epilepsy disorders and other neurological conditions, primarily Dravet Syndrome (also known as severe myoclonic epilepsy in infancy), and genetic epilepsy with febrile seizures plus (GEFS+)

& Ayton, S

Diaz, I., Namkoong, J., Wu, J

The female mice (homozygous for Hba tm1(HBA)Tow and heterozygous for Hbb tm2(HBG1,HBB*)Tow and Hbb tm3(HBG1,HBB)Tow [h/h:: A / S ], sickle-cell trait mice) and male mice (homozygous for both Hba tm1(HBA)Tow and Hbb tm2(HBG1,HBB*)Tow [h/h:: S / S ], sickle SCD mice) were bred to generate SCD mice

Compared with Cd treatment, C i in leaves of Tiannong 9 increased by 23.22%, and C i in leaves of Fenghe 6 decreased by 14.26% treated with Hemin