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In asymptomatic cases, immediate intervention is inadvisable

Recently, Koussiouris and colleagues found that some lipids (lysophosphatidylcholine and sphingomyelin) and other metabolites predict high disease activity from both low and moderate 29

Nature 481 , 469474 (2012)

Scioli MG, Storti G, DAmico F, Rodrguez Guzmn R, Centofanti F, Doldo E, Miranda EMC, Orlandi A (2020) Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets