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Aguzzoli CS, Anstey KJ, Atri A et al (2024) World Alzheimer Report 2024: Global changes in attitudes to dementia

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Retrograde Mitochondrial-Nuclear Signaling One interesting feature of MOTS-c biology is that MOTS-c seems to travel to the nucleus of cells under conditions of stress and alter the expression of nuclear genes that control antioxidant defences as well as metabolic programs