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The absolute number of monocytes ( Supplementary Table 2 ) dropped to one fifth of the initial level immediately after LPS administration and remained at this level for 3 days, before recovering until 7 d pi

Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite

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490 Leptin, which is secreted by adipose tissue, regulates energy homeostasis, with increased fat reserves typically leading to increased circulating leptin levels

This dynamic response suggests that upon TCR activation, T cells undergo rapid rewiring of their sterol metabolism, which is characterized by increased sterol synthesis and uptake to support membrane synthesis during T cell expansion