Today vitamin C is a popular dietary supplement, and due to improved accessibility to fruits, vegetables and vitamin supplements, disability and death from scurvy are rare
The combination of metformin and doxorubicin led to doxorubicin sensitization in R-HepG2 cells, a resistant HCC cell line with a CSC phenotype [196]
Protein targets and antibody information used in scMEP are listed in supplementary table 2

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In parallel, reductions in SCFA-producing bacteria and lower butyrate/acetate concentrations have been reported, although the clinical relevance of these changes is largely inferred from the well-established roles of SCFAs in colonic physiology