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doi:10.1016/j.parkreldis.2024.107015

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Furthermore, IIAEK significantly increased the liver CYP7A1 (the rate-limiting enzyme for bile acid synthesis 20 ) protein level and significantly decreased the liver NPC1L1 protein level in WT mice compared to the levels in the WT, Control group (Fig

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As previous international studies have noted, the true prevalence rate of restless legs syndrome may actually be underestimated due to a variety of factors, including the belief that restless legs are a minor ailment that doesn't require medical attention, the fear that affected individuals will be shunned in some cultures, and the absence of symptoms when testing a patient while they are awake (Yeh et al., 2016)