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Epigenetics, 1(2), 76-80

This evidence was strengthened by studies in vivo in which manipulation of calpastatin levels, an endogenous calpain inhibitor, led to modulation of the neurological phenotype seen in a SCA3 mouse model, as well as of mutant ATXN3 aggregation and neurodegeneration, consistent with a role for calpain activation in pathogenesis [50, 52]

Kapoor B, Kapoor D, Gautam S, Singh R, Bhardwaj S (2021) Dietary Polyunsaturated Fatty Acids (PUFAs): Uses and Potential Health Benefits

Liposomal delivery acts like a protective vehicle

Anthocyanidins and cyanidin-3-glucoside (C3G) found in bilberry have been shown in preclinical studies to protect eye health