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Melectin penetrates cancer cell membranes and binds intracellular DNA or RNA, inhibiting replication and inducing apoptosis ( 5.3 New function of clinical antibiotics and anticancer drugs Dactinomycin, also known as actinomycin D, is an antibiotic isolated from the bacterium Streptomyces parvulus

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It found numerous biases and confounders in the available data

Then, the cartridge was dried under vacuum with a defined nitrogen flow (5.0, Nippon Gases, Dsseldorf, Germany) for approximately 25 min

Given that ARID1A-negative cancer cells have been previously shown to be more susceptible to inhibition of glutathione synthesis compared to ARID1A-positive cancer cells, we next sought to determine whether EN25 selectively impairs cell viability of ARID1A-negative A2780 ovarian cancer cells, compared to ARID1A-positive RMG-1 ovarian cancer cells