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In this study we use a multi-omics approach to determine the relationship of ADA2 activity with metabolic and inflammaotry pathways associated with macrophage activation and fibrosis

10.3390/life11090986 30

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doi:10.1155/2013/928290 42

This is particularly important in the brain, where elevated iron levels can lead to the production of ROS, contributing to neuronal damage and neurodegeneration (256,257)