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Trimethylamine N-Oxide: the good, the bad and the unknown

We envision that exosomes from healthy human lung or lung secretions with the inherent expression of ACE2 may provide a specialized therapeutic strategy that harbors target-homing effects and native antiviral properties, which could alleviate host inflammation and reduce viral replication in SARS-CoV-2 infection, promising for emerging SARS-CoV-2 variants

Additionally, regional variability in astrocytic responses may contribute to these findings, as the hippocampus examined by Ghoneim et al

[DOI] [PubMed] [Google Scholar] [97].Setoguchi S, Hirooka Y, Eshima K, Shimokawa H, Takeshita A

In this respect, it still stands its ground regardless of the development of newer medications in this rapidly evolving field