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Among the flavonoids, epigallocatechin-3 gallate (EGCG), a catechin rich in green tea, when administered to male rats at doses of 25, 50 and 100 mg/kg of body weight, showed an antithyroid activity, which was manifested by reduced activity of thyroid peroxidase and 5-deiodinase I and increased activity of the thyroid sodium-potassium pump

Met- S -O and Met- R -O refer to the ( S -) and ( R -) configurations of the sulfur, respectively

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