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We also used homozygous APOE3 and APOE4 mice, which do not reflect the full spectrum of APOE allele combinations in humans (Hana Saddiki et al., 2020)

They achieve this by targeting ferroptosis and inhibiting GPX4 ubiquitination, thereby enhancing antioxidant pathways

Following replication inside hepatocytes, merozoites are released into the blood where they invade erythrocytes to initiate the blood stage of the parasite lifecycle