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This "fragment + stabiliser" method is a Russian methodological signature, widely used subsequently by the Khavinson, Myasoedov groups, and more recently by Chinese and Indian teams

Additionally, SOD levels could serve as potential biomarkers for assessing skin cancer risk and prognosis, highlighting the enzymes importance in skin cancer prevention and treatment strategies

Such a response is reminiscent of that of the daf-2 mutant, where daf-16 and xbp-1 act to maintain ER homeostasis (and increasing the lifespan) without inducing HSPs 66

These findings support the safety and potential disease-modifying effects of FUS-mediated BBB opening in early-stage AD, although larger trials are warranted to establish clinical efficacy (Rezai et al., 2024)