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Given the small sample sizes and methodological constraints, the results should be interpreted as exploratory, but indicative of important trends

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Levodopa-carbidopa intestinal gel, also referred to as Duodopa, is an option for those with advanced PD, compared to oral L-DOPA, with the intestinal gel showing less motor fluctuations and dyskinesias, though they are not completely eliminated

doi: 10.3892/ol.2021.12452 49 LiYLiLHlscherC

81,134,141 ) In addition to perturbations in endogenous RSS metabolism, excessive H 2 S generated via bacterial cysteine desulphydrase from gut microbiota species such as Fusobacterium nucleatum has been linked to the development of colorectal cancer