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The complete removal of intronic regions flanking the GAA repeats showed the most significant restoration of FXN expression, compared to elimination of only the GAA tract, offering a potential therapeutic strategy for FRDA

10.1038/nprot.2008.80 75 MitchellJ

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167-169 In a randomized controlled crossover trial in 52 postmenopausal women with fibromyalgia, 50 mg of DHEA per day for three months raised DHEA-S levels from 51.6 to 165.8 mcg/dL