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T cells that express the cell-surface protein CD4 are divided into two subsets depending on the particular cytokines that they produce: T helper (Th)1 cells are primarily involved in activating macrophages and inflammatory responses, and Th2 cells are primarily involved in stimulating antibody production by B cells (4)

doi: 10.1093/toxsci/53.2.340

In addition to the other adverse manifestations of MS, pain is a common symptom that affects 70% of sufferers

Plos ONE 7 , e52570 (2012)

The constant auditory stimulation can severely disrupt concentration, making it difficult to perform at work, engage in conversations, or simply enjoy quiet moments