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On the other hand, aberrant DNA methylation can contribute to disease conditions like inflammatory diseases, precancerous lesions and cancer (9 11)

2019;5:eaaw2238

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Chu EK, Ribeiro SP, Slutsky AS

pylori and N-methyl-Nnitro-Nnitrosoguanidine (MNNG), the downstream pathways P53, Wnt, Ras, and mTOR are activated by ROS ( via ROS-triggered ER stress, and promoting the development of gastric cancer ( H pylori CagA produces cells with oxidative DNA damage by inducing spermine oxidase (SMO), and a portion of these cells are apoptosis-resistant and therefore highly susceptible to developing cancer ( H pylori infection