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This perspective, supported by the Lancet Commission on Dementia Prevention, Intervention and Care, is grounded in large-scale observational studies linking factors such as low educational attainment, midlife hearing loss, hypertension, obesity, smoking, depression, diabetes, physical inactivity, and social isolation to increased dementia risk (103)

doi: 10.1038/s41439-020-0102-6 276 YoonS

L-JN performed the experiments and drafted the manuscript

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